![]() ![]() The protein browser displays the antigen location on the target protein(s) and the features of the target protein. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis. Induces the formation of apical actin-dependent microvilli. ![]() Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Functions as an anti-adhesive mo lecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. ![]() Involved in the regulation of both adhesion and cell morphology and cancer progression. Useful information about the protein provided by UniProt. ![]()
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